Hexahydrocannabinol (HHC) is an intoxicating cannabis compound that gets you high. Its effects are less potent than Delta-9-THC, inducing mild euphoria and relaxation in small to medium doses.
HHC is a great cannabinoid for beginners who want to experience a subtle but noticeable high. Experienced users can mix HHC with delta-8 THC for stronger, more intense euphoric effects - a small dose of CBD can also provide gentle relaxation. It's important to note that HHC is likely to cause a positive or false positive drug reading, so make sure you don't have any upcoming drug tests.
The central theses:
- HHC is an intoxicating natural or semi-synthetic cannabinoid that gets you high. It is weaker than Delta-8 and Delta-9 and is suitable for beginners. We recommend a dose of 10 mg to begin with.
- The effects of HHC can include mild euphoria, relaxation, and physical sensations in small and medium doses (1-10 mg). Larger doses (10+ mg) can cause stronger effects and a higher risk of negative short-term side effects such as anxiety, paranoia, and physical discomfort. Some users may also experience memory loss, nausea, and nausea.
- There is very little research on the benefits of HHC. However, two HHC analogs (LYR-7 and LYR-8) promote antiproliferation and helped reduce tumor growth. HHC likely shares the same benefits as Delta-9 and Delta-8 due to its molecular similarity and ability to bind to CB1 receptors.
- The onset of action of HHC is 5-10 minutes when smoking or vaping HHC and up to 60 minutes when ingested orally, e.g. HHC gummies. The effects of smoking or vaping HHC products can last up to four hours, and up to six hours if taken by mouth.
- HHC is likely to trigger a positive or false positive drug test result due to product contamination or the similarity of HHC metabolites to delta-9 metabolites. HHC detox is impossible. You cannot completely remove HHC from your fat cells.
Does HHC get you high?
Yes, HHC gets you high. It is an intoxicating cannabinoid and homologue of Delta-9, meaning that they have and can have nearly identical molecular structuresactivatethe cannabinoid receptors of your endocannabinoid system, specifically cannabinoid 1 (CB1). However, HHC has a weaker CB1 binding affinityto the Delta-9s, making it a more suitable option for beginners.
HHC's CB1 activation behavior causes a release of special neurotransmitters (endocannabinoids) in your brain. Endocannabinoids are chemical messengers that carry signals from nerve cells (neurons) to target cells. This activity is responsible for regulating several biological processes such as mood, sleep, pain, memory, and other benefits, and disrupts several mental and physical functions.
The activity of THC in the cerebellum and basilic ganglia of your brain can cause balance, coordination, and reaction timechallenges. Likewise, the THC receptor binding in the hippocampus induces short-termmemory loss, and the low presence of CB1 receptors in brainstem nuclei may be responsibleminimal toxicitywhen consumed in overdose.
Is HHC stronger than THC?
HHC is probably less potent than THC with aweakerCB1 binding affinity. Research shows that the structurally similar HHC analog is roughly 9-hydroxyhexahydrocannabinol (9-OH-HHC).10-25 malless powerful than Delta-9.
RELATED: HHC vs THC: What's the difference?
Anecdotal evidence from users online suggests that an HHC high and its associated effects are 70-80% weaker than those associated with Delta-9. However, these weaker effects don't mean you can eat a whole packet of HHC gummies in one sitting. You will still experience a high – maybe even an uncomfortable one.
What is HHC?
HHC is short for hexahydrocannabinol, a naturally occurring minor cannabinoid present in cannabis, including hemp and marijuana. Manufacturers can also synthesize HHC through THC hydrogenation, a process that combines high pressure, molecular hydrogen, and a catalyst such as nickel or platinum in a chemical reaction. This reaction causes the THC double to break and become unstable. The introduction of hydrogen stabilizes its molecular structure again and makes it more resistant to heat and UV light. Renowned cannabis scientist Roger Adams was the firstsynthesizeHHC in 1947. Researchers have proved that HHC aby-product of degradationfrom THC.
RELATED: What is HHC and what are its effects?
How does HHC feel?
How HHC makes you feel is purely subjective. Some users report mild euphoria, physical relaxation, and mental focus. In contrast, other users report sedation and drowsiness. Higher doses, beyond your tolerance level, can rarely cause negative but non-life-threatening side effects such as anxiety, stress, memory loss, and nausea. Because of these side effects, we always recommend that you start with the lowest dose, especially if you are a beginner.
CBD Oracle recently collected data on its readers using HHC and the responses were mixed.
One reader claims that HHC "hit faster" with more "sativa-like" effects. Cannabis folklore online states that common sativas induce a "mind high" with effects such as sedation, couch-lock, anxiety relief and relaxation. However, another reader states that HHC promotes "clear mind", positive euphoric sensations and energy. These effects are often associated with indica cannabis strains.
A constant among HHC users is that it gives them a more subtle and less overpowering high without too much anxiety or paranoia.
How long does an HHC high last?
An HHC high lasts between 2 and 6 hours, about the same as Delta-9 and Delta-8. Several factors affect the duration of your high, including dose, dosing method, metabolic rate, and body fat percentage.
Suppose you smoke an HHC flower product. The onset of action is about 5-10 minutes and can last up to four hours. Conversely, HHC gummy candy takes up to 60 minutes and can last up to six hours (sometimes longer).
This change in the onset and duration of your high is largely dependent on how the body absorbs HHC.
HHC gums travel through your digestive system and are absorbed through your intestinal walls, eventually entering your bloodstream and metabolized by your liver. HHC is then redistributed back into your bloodstream after the metabolization process. Food intake and how much food is in your stomach affect HHC absorption. The more food there is in your belly, the slower the rate of absorption.
On the other hand, HHC flower enters your bloodstream through tiny air sacs lining your lungs, bypassing the digestive system entirely and causing a faster onset of effects. Research shows that HHC and other THC isomers take 10-20 seconds to travel from the lungs to the brain.
How Much HHC Should You Take?
Although HHC is weaker than Delta-9, novice cannabis users should consume as little HHC as possible. The reason for this caution is that you simply don't know how a cannabinoid reacts in your body.
We recommend around 2-5 mg to start with. If the effects aren't noticeable, wait an hour and consume a milligram or two. If you are an experienced cannabis user, we recommend a starting dose of between 10 and 25mg. If you feel very few effects, try another 5 mg an hour or two after the first dose. If you want to get super high, anything over 25 mg is optimal, but not recommended. A dose greater than 25 mg may be too strong. Remember:Start low, go slow.
What are the benefits of HHC?
Aside from a subtle but noticeable high suitable for cannabis beginners, what are the benefits of HHC? HHC may have some, many of which are likely similar to Delta-9 and other THC isomers in that they activate your endocannabinoid system's CB1 receptors. These benefits can include pain relief, sleep promotion, appetite stimulation, and stress reduction.
preclinicalResearchshows that the synthetic HHC analogs LYR-7 and LYR-8 significantly reduced tumor growth in mouse subjects, prevented the formation of new blood vessels and reduced the growth of cancer cells.
Will HHC show up on a drug test?
HHC can cause a positive or false positive drug test result. Users on Reddit and other social sites claim that a standard drug test detected HHC in their body, resulting in a positive result. However, other users have had different experiences and failed a drug test after HHC use.
The science behind HHC and a failed drug test result are inconclusive, but we can safely assume that HHC products are likely to trigger a positive or false positive reading for two reasons:
1) HHC metabolites are similar to those produced by Delta-9-THC.
Drug tests look for the delta-9 metabolites 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid (9-carboxy-THC) and 11-hydroxy-delta-9-tetrahydrocannabinol (THC-OH). Studies show that liver microsomes from animal subjects metabolize an HHC isomer to the metabolite 11-hydroxy-hexahydrocannabinol (11-OH-HHC), a minor delta-9 metabolite. Because delta-9 and HHC are metabolized to 11-OH-HHC, drug tests could detect the use of THC, leading to a positive result.
2) Cannabis producers can inadvertently cross-contaminate their HHC products with Delta-9.
Not all cannabis producers go the extra mile to ensure their HHC products are clean and safe for human consumption. Many low-budget dollar hunter companies cut corners, especially during the production phase, resulting in a higher incidence of delta-9 THC cross-contamination, even if the label doesn't state that THC is in the HHC product. So what happens when you consume these THC-contaminated HHC products? Well, you are unknowingly consuming varying amounts of THC. These amounts are likely to result in a failed drug test.
Can You Detox HHC From Your System?
No. You cannot flush, remove, or detoxify HHC from your system. Cranberry juice, green tea, special detox kits, and other related removal methods mask or hide HHC from drug testing.
Like Delta-9, HHC is fat-soluble andShopslocated in your adipose tissue (adipose tissue). Adipose tissue is made up of fat cells and is found all over your body. Time and abstinence is the only way to clear HHC and other THC isomers from fat cells. Alternatively, you can always remove every inch of fat tissue from your body, which is obviously impossible.
Can you overdose on HHC?
There has never been a case of HHC or any other cannabis compound causing an overdose. However, some of the negative side effects of HHC can feel like an overdose.
There have never been cases of overdose from ingestion of HHC or other organic cannabis compounds. However, if you take too much HHC, it can make you anxious and paranoid. This fear and paranoia can make youfearan overdose orfeellike you're overdosing It's important to remember that these feelings are safe and do not indicate a heart attack or overdose.
Stop using HHC if you are suffering from anxiety, stress or paranoia. Find a chair or bed in a dark, comfortable room and rest until the effects wear off. Take some CBD if you have any. CBD is anon-competitive negative allosteric modulatorof CB1 receptors. This modulating behavior means that HHC and other THC isomers are partially or completely prevented from binding to CB1, reducing a euphoric high. We recommend taking CBDBeforeHHC dosage for a more relaxed experience.
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We've found that HHC gets you high, so why not try it yourself? There are many HHC products available on the market. Some great, some not so great. We recommend givingHHC Vape CartsCheck them out, they're quick, easy, efficient and effective to get you high with a nice dose of relaxation and euphoria. If vaping isn't your thing, no problem. We have a comprehensive list of the bestHHC gummieson the market, all verified by our team of experts.